Subsystem: Lipoprotein Biosynthesis
This subsystem's description is:
The genes responsible for posttranslational modification and processing of bacterial lipoprotein precursors
For more information, please check out the description and the additional notes tabs, below
| Literature References | Lipoprotein synthesis in mycobacteria. Rezwan M Microbiology (Reading, England) 2007 Mar | 17322184 |
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| Diagram | Functional Roles | Subsystem Spreadsheet | Description | Additional Notes | |||||||||
The genes responsible for posttranslational modification and processing of bacterial lipoprotein precursors Lipoproteins are a functionally diverse class of secreted bacterial proteins characterized by an N-terminal lipid moiety. The lipid moiety serves to anchor these proteins to the cell surface. Lipoproteins are synthesized as pre-prolipoproteins and mature by post-translational modifications. Precursor lipoproteins are post-translationally modified by phosphatidylglycerol–pre-prolipoprotein diacylglyceryl transferase (Lgt) and prolipoprotein signal peptidase (LspA). In Gram-negative bacteria and probably also in mycobacteria, lipoproteins are further processed by apolipoprotein N-acyltransferase (Lnt). (See Illustration) | |||||||||||||
